If you’ve been looking into regenerative treatments for hair loss, joint pain, or skin rejuvenation, you’ve probably come across PRP (Platelet-Rich Plasma) and PRGF (Plasma Rich in Growth Factors).
Both treatments use your own blood to stimulate healing and tissue regeneration, but they’re not the same.
PRP is widely known for hair restoration and sports injuries, while PRGF is often used for chronic conditions and wound healing.
This guide breaks down PRGF vs PRP in simple terms so you can decide which treatment is best for your needs.
What Is PRP?
PRP, or Platelet-Rich Plasma, is a treatment that isolates the platelets in your blood and injects them back into the body to speed up healing.
Platelets contain growth factors that help repair tissues, improve blood flow, and reduce inflammation.
How PRP Is Made
- A small amount of blood is drawn from your arm.
- The blood is spun in a centrifuge, separating the platelets from other components.
- The concentrated platelet-rich plasma is injected into the treatment area.
What PRP Helps With
- Hair restoration – PRP stimulates hair follicles, promoting thicker, stronger hair.
- Joint pain and sports injuries – Helps with arthritis, tendonitis, and ligament damage.
- Skin rejuvenation – Increases collagen production, reducing fine lines, scars, and wrinkles.
What Is PRGF?
PRGF, or Plasma Rich in Growth Factors, is similar to PRP but goes through an extra purification process that removes inflammatory cells.
This makes PRGF less irritating and may provide longer-lasting growth factor release.
How PRGF Is Made
The process is almost identical to PRP, but PRGF undergoes an additional centrifuge step to remove white blood cells and pro-inflammatory elements.
This makes it gentler on tissues.
What PRGF Helps With
- Orthopedic injuries and arthritis – Helps regenerate cartilage and reduce joint pain.
- Dental and oral surgery – Speeds up healing after tooth extractions or implants.
- Chronic wound healing – Used for burns, ulcers, and surgical recovery.
PRGF vs PRP: Key Differences
| Feature | PRP | PRGF |
| Platelet Concentration | High | Moderate |
| Growth Factor Release | Immediate | Sustained Over Time |
| Inflammation | May Cause Mild Inflammation | Less Inflammatory |
| Best Uses | Hair Restoration, Joint Pain, Skin Rejuvenation | Chronic Pain, Dental, Long-Term Healing |
Which One Works Better?
- PRP delivers fast results, making it the top choice for hair restoration, sports injuries, and skin rejuvenation.
- PRGF works more slowly but may provide longer-lasting benefits, especially for arthritis, surgery recovery, and wound healing.
PRGF vs PRP for Hair Restoration: Which One Works Best?
Both PRP and PRGF are used for hair growth, but PRP is the better choice for most people because:
- It contains a higher concentration of platelets, which stimulates hair follicles more effectively.
- PRGF may reduce inflammation, but it doesn’t boost follicle activity as quickly as PRP.
- Studies show that PRP is highly effective for reversing hair thinning and promoting regrowth.
Why Choose PRP for Hair Loss at First Choice Medical?
- Uses advanced PRP technology to maximize hair regrowth.
- Minimally invasive with no downtime.
- Safe and effective for both men and women experiencing hair thinning.
PRGF vs PRP for Joint Pain
If you’re dealing with joint pain or a sports injury, both PRP and PRGF can help, but they work differently:
- PRP is best for faster healing – Athletes and active individuals benefit from its quick-acting growth factors.
- PRGF is better for long-term recovery – People with arthritis or chronic joint conditions may prefer PRGF for sustained healing over time.
- Some doctors combine PRP and PRGF to enhance the benefits of both treatments.
Which One Should You Choose?
Here’s a quick way to decide:
| Condition | Best Treatment |
| Hair Loss | PRP (More effective for follicle stimulation) |
| Sports Injuries | PRP (Faster recovery for active individuals) |
| Arthritis & Chronic Pain | PRGF (Longer-lasting pain relief) |
| Skin Rejuvenation | PRP (Boosts collagen for younger-looking skin) |
| Dental or Surgical Healing | PRGF (Speeds up recovery) |
For most people, PRP is the better option for hair loss, skin rejuvenation, and sports injuries, while PRGF is best for chronic conditions.
Consulting with a medical professional can help determine the right choice.
How First Choice Medical Can Help with PRP Treatments
At First Choice Medical, we specialize in PRP therapy to help patients achieve natural healing and restoration.
- PRP treatment for Hair Restoration – Advanced treatment for hair thinning and regrowth.
- PRP for Joint Pain – Reduces pain and accelerates healing for injuries.
- PRP for Skin Rejuvenation – Helps smooth wrinkles, scars, and fine lines.
Conclusion: PRGF vs PRP
PRP and PRGF both use your body’s natural healing abilities, but they have key differences:
- PRP is best for fast, targeted results, making it ideal for hair loss, joint pain, and skin rejuvenation.
- PRGF is better for long-term healing, especially for arthritis, dental procedures, and chronic conditions.
- PRP therapy at First Choice Medical can help with hair loss, joint pain, and skin health.
If you’re considering PRP therapy, contact us today to learn how it can help you.
FAQs: PRGF vs PRP
Which is better, PRGF or PRP?
It depends on your needs. PRP is better for hair restoration, sports injuries, and skin rejuvenation because it delivers high concentrations of growth factors quickly. PRGF is better for long-term healing and chronic conditions like arthritis or dental recovery since it releases growth factors more gradually with less inflammation.
What is the difference between PRP and PRGF?
PRP and PRGF are both platelet-based regenerative therapies, but PRGF goes through an additional purification process to remove inflammatory cells. This makes PRGF less inflammatory and better for long-term healing, while PRP is more concentrated and acts faster, making it ideal for hair restoration, joint pain, and aesthetic treatments.
Can PRGF regrow hair?
PRGF contains growth factors that support tissue repair and scalp health, but it is not as effective as PRP for stimulating hair follicles and regrowing hair. PRGF may be helpful in reducing inflammation and improving scalp conditions, but PRP remains the preferred treatment for hair restoration.
Can PRP regrow hair?
Yes, PRP is widely used for hair restoration because it contains a high concentration of growth factors that stimulate hair follicles, increase blood flow to the scalp, and promote thicker, healthier hair growth. Many clinical studies and real-world results support PRP as an effective treatment for hair loss in both men and women.
What are the three types of PRP?
The three main types of PRP are Pure PRP (P-PRP), Leukocyte-Rich PRP (L-PRP), and Leukocyte-Poor PRP (LP-PRP). Pure PRP (P-PRP) contains platelets but fewer white blood cells and is commonly used in aesthetics and hair restoration. Leukocyte-Rich PRP (L-PRP) contains white blood cells, which can increase inflammation and is often used in sports injuries and joint treatments. Leukocyte-Poor PRP (LP-PRP) has fewer white blood cells and is used in cases where reducing inflammation is a priority.
